HA (Hyaluronic Acid) IMMERSE Serum™

A Daily Hydration Breakthrough
A breakthrough hyaluronic acid serum that delivers instant hydration for smoother, more radiant-looking skin — while helping amplify skin's hyaluronic acid levels over time. Read full benefits

SKIN CONCERNS: Aging Skin | Dehydrated Skin | Dry Skin

Size: 1.0 Fl. Oz. 29.6 mL

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Benefits of HA IMMERSE Serum

Benefits of HA IMMERSE Serum

  • Helps instantly boost skin hydration at the surface for smoother, more radiant looking skin.
  • Proprietary Octapeptide-45 helps the skin’s ability to naturally increase its own high-molecular hyaluronic acid production deep within for long-term skin plumping, anti-aging, and hydration benefits.
  • Provides both instant and long-lasting results.
  • Helps to increase natural levels of hyaluronic acid in the skin which works to minimize the appearance of fine lines and wrinkles.
  • Recommended for daily use and complements dermal fillers.
  • Winner of New Beauty “Best Hyaluronic Acid” award.
  • Winner of Oprah Daily's 2022 O-ward for “Best Hydrating Serum” .
  • Skin Concerns: Dehydrated Skin; Dry Skin; Dull Skin



Octapeptide-45 icon Octapeptide-45 Helps to stimulate HAS2 in fibroblasts, an enzyme that stimulates HA production.
Silver Mushroom icon Silver Mushroom Extract Provides and encourages skin hydration.
Hexapeptide-11 icon Hexapeptide-11 Helps prevent the production of enzymes that break down HA, helping your body’s ability to preserve its natural HA.


Smoother, Calmer, More Radiant-Looking Skin After 4 Weeks of Use

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Female, Age 48
ALASTIN Skincare® Regimen: Gentle Cleanser, HA IMMERSE Serum, & SilkSHIELD SPF 30+, all products used twice daily (except sunscreen used morning only)
Imaging Equipment & Analysis: VISIA (Canfield, Scientific, Parsippany, NJ).
Reference: Data on file at ALASTIN Skincare®. Individual results may vary. Photographs are unretouched. Photography courtesy of Deanne Robinson, MD; Modern Dermatology, Westport, CT.

Improvement In The Appearance of Redness and Texture Within 8 Weeks

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Female, Age 38 ALASTIN Skincare regimen: Gentle Cleanser, HA IMMERSE Serum™, Ultra Light Moisturizer (post Week 4 due to dryness with weather change), & SilkSHIELD SPF 30+, all products used twice daily (except sunscreen used morning only) Imaging Equipment & Analysis: VISIA®-CR (Canfield Scientific Inc., Parsippany, NJ) Reference: Multi-Center Clinical Evaluation of a Topical Hyaluronic Acid Serum in Facial Skin, n=46; photographs are unretouched. Individual results may vary. Photography courtesy of DMR Research, Westport, CT.
Data on file at ALASTIN Skincare

of study participants agreed HA IMMERSE made their skin feel smooth immediately after applying* +
of participants agreed that HA IMMERSE replenished the moisture in their skin after 4 weeks of use+
of participants agreed HA IMMERSE improved the overall appearance of their skin after 4 weeks of use+
+Subject questionnaire completed at weeks 2, 4.
*Subject assessment completed 15 minutes post application.


Pair HA IMMERSE Serum™ with these products for the ultimate anti-aging regimen.

Combat Fine Lines & Wrinkles

Addresses all visible signs of aging on the face.

Protect & Glow

Powerful sun protection with a hint of tint.

Correct Tone & Texture

Helps smooth skin texture and improve skin tone.



The hydrating power of HA IMMERSE Serum™, seen through hydration mapping, shows improvement over time. Blue color represents the volumetric ratio of water in the skin tissue.

*Data on file at ALASTIN Skincare



  • Apply 1-2 pumps twice a day (morning and evening).
  • Apply HA IMMERSE as the FIRST product in your daily regimen after cleansing.
  • Avoid getting in the eyes. If contact occurs, rinse thoroughly with water.



To open, twist the top silver collar of the bottle until the pump emerges completely and clicks into place. To close, twist the opposite direction.

After washing your face, apply HA IMMERSE to your face and neck before applying any other product morning and night.

Dry skin is a skin type that underproduces sebum (oil), is often consistent throughout the year, and usually feels dry all over the face and body. In contrast, dehydrated skin is a skin condition that lacks water, that any skin type may experience. It may come and go throughout the year with seasonal changes.

No, HA IMMERSE Serum should be used to boost your anti-aging regimen. HA IMMERSE is a hydrating serum, whereas Restorative Skin Complex is an all-in-one anti-aging solution.

Yes, HA IMMERSE Serum complements dermal fillers and is recommended for daily use.

HA IMMERSE Serum can safely be used on the neck and decollete. We have not tested the product directly on the eyes or eyelids. Please refer to your provider.

Based on your unique skin type and the season where you live,  you may still need a moisturizer. Alastin offers two moisturizers, Ultra Nourishing Moisturizer and Ultra Light Moisturizer. Please refer to your provider to discover which one would be best for you.

No, you don’t need to wet your fingertips before using HA IMMERSE Serum.

Physician insights

“HA IMMERSE Serum™ is an important addition to any daily skincare regimen. We know from clinical studies the product makes an impact instantly, but the results get better and better as time goes on and their skin is more hydrated and radiant.”

Dr Melanie Palm, Dermatologist