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Peptides are the foundation for many of our science-backed skincare products. Before “peptides” was a buzzword in the industry, ALASTIN Skincare® developed our patented TriHex Technology®.
TriHex Technology includes Tripeptide-1 and Hexapeptide-12 that support the REMOVAL of aged collagen and elastin to help jump-start the skin’s natural rejuvenation process. Collagen and elastin break down and clump together due to photodamage and aging, which can slow down the production of new, healthy collagen and elastin in the deepdermal structure of the skin.
TriHex Technology helps the skin REBUILD healthy collagen and elastin to support visible changes at the surface level. TriHex Technology helps restore the optimal skin environment and create room for new, healthy collagen and elastin by removing the damaged fragments.
With daily use, TriHex Technology helps to REPLENISH new, healthy collagen and elastin and to clear the damaged fragments to maintain healthy skin from the inside out on an ongoing basis.
Product | Date | Title | Publication | Download |
---|---|---|---|---|
C-RADICAL Defense Antioxidant Serum | Jan 2024 | Vitamin C, lactoferrin and elastin—Advancing the science | Journal of Cosmetic Dermatology | Download |
A-LUMINATE Brightening Serum | Jan 2024 | Extension Phase of a Multi-Center, Randomized, Blinded Clinical Study Evaluating the Efficacy and Safety of a Novel Topical Product for Facial Dyschromia | JDD | Download |
C-RADICAL Defense Antioxidant Serum | Oct 2023 | Multicenter evaluation of a topical antioxidant serum | Journal of Cosmetic Dermatology | Download |
C-RADICAL Defense Antioxidant Serum | Oct 2023 | Antioxidants with proven efficacy and elastin-conserving vitamin C—A new approach to free radical defense | Journal of Cosmetic Dermatology | Download |
A-LUMINATE Brightening Serum | April 2023 | A Multi-Center, Randomized, Blinded Clinical Study Evaluating the Efficacy and Safety of a Novel Topical Product for Facial Dyschromia | Journal of Drugs and Dermatology | Download |
Regenerating Skin Nectar | Dec 2022 | A Single Center, Prospective, Randomized, Blinded Study to Evaluate the Efficacy and Safety of a Topical Tripeptide/Hexapeptide Anhydrous Gel When Used Pre- and Post- Hybrid Fractional Laser for the Treatment of Acne Scars | Clinical, Cosmetic and Investigational Dermatology | Download |
Restorative Eye Treatment, INhance Post-Injection Serum | Dec 2022 | A Multi-Center Evaluation of Restorative Eye Treatment and INhance With Trihex Technology to Improve Aesthetic Outcomes When Used Pre- and Post-Blepharoplasty | ASJ | Download |
A-LUMINATE Brightening Serum | Nov 2022 | Advances in Pigmentation Management: A Multipronged Approach | JDD | Download |
TransFORM Body Treatment | October 2022 | A Single Center, Randomized, Double-Blind Study to Evaluate TransFORM Body Treatment with TriHex Technology in Combination with Radiofrequency Microneedling to the Suprapatellar Region | Download | |
Restorative Skin Complex | Aug 2022 | Effects of a Topical Anti-aging Formulation on Skin Aging Biomarkers | Download | |
HA IMMERSE Serum | July 2022 | Multicenter Evaluation of a Topical Hyaluronic Acid Serum | Journal of Cosmetic Dermatology | Download |
ReFORM & RePAIR Complex | June 2022 | A Multicenter, Randomized, Double-Blind, Split-Body Clinical Trial Evaluating the Efficacy and Outcomes of a Topical Product Pre and Post Aesthetic Surgical Body Procedures | Aesthetic Surgery Journal | Download |
HA IMMERSE Serum | April 2022 | Designing topical hyaluronic acid technology— Size does matter… | Download | |
Regenerating Skin Nectar, TransFORM Body Treatment | July 2021 | Topical Skin Treatment and Its Influence on Surgical Healing: Review of Literature and Underlying Physiology | Download | |
TransFORM Body Treatment | May 2021 | Evaluating a Topical Adjunctive Post Submental ATX-101 (Deoxycholic Acid) Injections for Improved Recovery: A Single-Center, Double-Blind, Randomized Controlled Pilot Study | Download | |
TriHex Technology | March/April 2021 | Tripeptide/Hexapeptide Topical in Esthetics: Evidence behind the Skincare Formulation | SkinMed | Download |
TransFORM Body Treatment | February 2021 | Prospective, Randomized, Comparative Study of the Cutaneous Effects of a Topical Body Treatment Compared to a Bland Moisturizer | Aesthetic Surgery Journal | Download |
Regenerating Skin Nectar | December 2020 | Evaluating the Efficacy, Tolerability, and Outcomes of Topical Tripeptide/Hexapeptide Formulations Before and After Liposuction of the Medial Thighs | The Aesthetic Society | Download |
TriHex Technology | Nov/Dec 2020 | Combination Tripeptide/Hexapeptide Serum with 1540 nm Nonablative Fractional Laser for the Treatment of Striae Distensae: A Pilot Study | Dermatology Case Report | Download |
INhance Post-Injection Serum | November 2020 | New approaches to skin photodamage histology— Differentiating 'good' versus 'bad' Elastin | Journal of Cosmetic Dermatology | Download |
TransFORM Body Treatment | November 2020 | An Analysis of Patient-Reported Recovery Outcomes of Topical Tripeptide/Hexapeptide Formulations Utilized in a Prospective Randomized Double-Blind Split Neck and Body Study | The Aesthetic Society | Download |
Regenerating Skin Nectar | Sept 2020 | Tripeptide and hexapeptide topical as adjunct to nonablative fractional resurfacing for photodamage: A randomized splitface trial | Journal of Cosmetic Dermatology | Download |
Regenerating Skin Nectar | Feb 2021 | Prospective, Randomized, Comparative Study of the Cutaneous Effects of a Topical Body Treatment Compared to a Bland Moisturizer | Download | |
Regenerating Skin Nectar, TransFORM Body Treatment | May 2020 | Gene Expression Changes in the Skin of Patients Undergoing Medial Thigh Liposuction With Pre-Surgical and Post-Surgical Application of Topical Products | Download | |
INhance Post-Injection Serum | March 2020 | Developing a Topical Adjunct to Injectable Procedures | JDD | Download |
TransFORM Body Treatment | January 2020 | Topical Treatment with Tripeptide and Hexapeptide Following Body-Contouring Procedures Improved Patient-Reported Recovery Outcomes | The Aesthetic Society | Download |
TransFORM Body Treatment | September 2019 | A randomized double-blind trial evaluating the efficacy and tolerability of topical body treatment with TriHex Technology® combined with abdomen cryolipolysis or radiofrequency procedures | Journal of Cosmetic Dermatology | Download |
Regenerating Skin Nectar | August 2019 | Pre- and Post-Procedural Care Best Practices To Enhance Energy-Based Treatment Outcomes | JDD | Download |
TriHex Technology | May 2019 | A topical regimen improves skin healing and aesthetic outcomes when combined with a radiofrequency microneedling procedure | Journal of Cosmetic Dermatology | Download |
TriHex Technology | April 2019 | Preoperative Skin Conditioning: Extracellular Matrix Clearance and Skin Bed Preparation, A New Paradigm | Aesthetic Surgery Journal | Download |
TransFORM Body Treatment | April 2019 | A Double-Blind Randomized Controlled Trial Evaluating the Efficacy and Tolerability of a Topical Body Treatment in Combination With Cryolipolysis Procedures | JDD | Download |
TransFORM Body Treatment | April 2019 | Non-Surgical Fat Reduction and Topical Modulation of Adipose Tissue Physiology | JDD | Download |
Restorative Skin Complex | June 2018 | A single-center clinical trial to evaluate the efficacy of a tripeptide/hexapeptide antiaging regimen | Dermatology Case Report | Download |
TriHex Technology | May/June 2018 | ALASTIN SKINCARE® TAKES THEIR PROPRIETARY TRIHEX TECHNOLOGY® TO THE NEXT LEVEL | PRIME | Download |
Regenerating Skin Nectar | May 2018 | Effects of anhydrous gel with TriHex peptides on healing after hybrid laser resurfacing | Download | |
Restorative Eye Treatment | Mar 2018 | A single-center, pilot study evaluating a novel TriHex peptide-and botanical-containing eye treatment compared to baseline | Download | |
Restorative Skin Complex | January 2018 | A single-center clinical trial to evaluate the efficacy of a tripeptide/hexapeptide antiaging regimen | Journal of Cosmetic Dermatology | Download |
Restorative Skin Complex | 2018 | A Tripeptide/Hexapeptide Anti-Aging Regimen that Targets Both Collagen and Elastin, and Improves both Physician and Subject Scoring of Facial Aesthetics | Dermatology Case Reports | Download |
Regenerating Skin Nectar, Restorative Skin Complex | September 2017 | Histological Changes Associated with Extracellular Matrix-Remodeling Topical Therapy | Dermatology Case Report | Download |
Regenerating Skin Nectar | July 2017 | Randomized, Split-Face/Decollete Comparative Trial of Procedure Enhancement System for Fractional non-Ablative Laser Resurfacing Treatment | JDD | Download |
TriHex Technology | March 2017 | A randomized, single-blinded trial of a tripeptide/hexapeptide healing regimen following laser resurfacing of the face | Journal of Cosmetic Dermatology | Download |
Regenerating Skin Nectar | April 2016 | Extracellular Matrix Modulation: Optimizing Skin Care and Rejuvenation Procedures | JDD | Download |
Regenerating Skin Nectar, Restorative Skin Complex, Restorative Eye Treatment | Oct 2016 | Recycling the Matrix | The Aesthetic Guide | Download |
Regenerating Skin Nectar | A randomized, investigator -blinded trial of alastin topical healing regimen following ipl and/or pdl with q-switch-alexandrite and fractionated co2 laser resurfacing of the face | Dermatology Case Report | Download | |
Regenerating Skin Nectar, Restorative Skin Complex | Histological changes associated with extracellular matrix-remodeling topical therapy | Dermatology Case Report | Download | |
Regenerating Skin Nectar | A single–center, randomized, investigator-blinded comparative trial, topical proprietary Procedure Enhancement System (PES) vs. a basic regimen (bland ointment and cream) pre and post-fractional non-ablative laser resurfacing treatment to the face/décolleté. | Dermatology Case Report | Download |
C-RADICAL Defense Antioxidant Serum
Jan 2024
Products:
Vitamin C, lactoferrin and elastin—Advancing the science
Publication:
Journal of Cosmetic Dermatology
A-LUMINATE Brightening Serum
Jan 2024
Products:
Extension Phase of a Multi-Center, Randomized, Blinded Clinical Study Evaluating the Efficacy and Safety of a Novel Topical Product for Facial Dyschromia
Publication:
JDD
C-RADICAL Defense Antioxidant Serum
Oct 2023
Products:
Multicenter evaluation of a topical antioxidant serum
Publication:
Journal of Cosmetic Dermatology
C-RADICAL Defense Antioxidant Serum
Oct 2023
Products:
Antioxidants with proven efficacy and elastin-conserving vitamin C—A new approach to free radical defense
Publication:
Journal of Cosmetic Dermatology
A-LUMINATE Brightening Serum
April 2023
Products:
A Multi-Center, Randomized, Blinded Clinical Study Evaluating the Efficacy and Safety of a Novel Topical Product for Facial Dyschromia
Publication:
Journal of Drugs and Dermatology
Regenerating Skin Nectar
Dec 2022
Products:
A Single Center, Prospective, Randomized, Blinded Study to Evaluate the Efficacy and Safety of a Topical Tripeptide/Hexapeptide Anhydrous Gel When Used Pre- and Post- Hybrid Fractional Laser for the Treatment of Acne Scars
Publication:
Clinical, Cosmetic and Investigational Dermatology
Restorative Eye Treatment, INhance Post-Injection Serum
Dec 2022
Products:
A Multi-Center Evaluation of Restorative Eye Treatment and INhance With Trihex Technology to Improve Aesthetic Outcomes When Used Pre- and Post-Blepharoplasty
Publication:
ASJ
A-LUMINATE Brightening Serum
Nov 2022
Products:
Advances in Pigmentation Management: A Multipronged Approach
Publication:
JDD
TransFORM Body Treatment
October 2022
Products:
A Single Center, Randomized, Double-Blind Study to Evaluate TransFORM Body Treatment with TriHex Technology in Combination with Radiofrequency Microneedling to the Suprapatellar Region
Publication:
Restorative Skin Complex
Aug 2022
Products:
Effects of a Topical Anti-aging Formulation on Skin Aging Biomarkers
Publication:
HA IMMERSE Serum
July 2022
Products:
Multicenter Evaluation of a Topical Hyaluronic Acid Serum
Publication:
Journal of Cosmetic Dermatology
ReFORM & RePAIR Complex
June 2022
Products:
A Multicenter, Randomized, Double-Blind, Split-Body Clinical Trial Evaluating the Efficacy and Outcomes of a Topical Product Pre and Post Aesthetic Surgical Body Procedures
Publication:
Aesthetic Surgery Journal
HA IMMERSE Serum
April 2022
Products:
Designing topical hyaluronic acid technology— Size does matter…
Publication:
Regenerating Skin Nectar, TransFORM Body Treatment
July 2021
Products:
Topical Skin Treatment and Its Influence on Surgical Healing: Review of Literature and Underlying Physiology
Publication:
TransFORM Body Treatment
May 2021
Products:
Evaluating a Topical Adjunctive Post Submental ATX-101 (Deoxycholic Acid) Injections for Improved Recovery: A Single-Center, Double-Blind, Randomized Controlled Pilot Study
Publication:
TriHex Technology
March/April 2021
Products:
Tripeptide/Hexapeptide Topical in Esthetics: Evidence behind the Skincare Formulation
Publication:
SkinMed
TransFORM Body Treatment
February 2021
Products:
Prospective, Randomized, Comparative Study of the Cutaneous Effects of a Topical Body Treatment Compared to a Bland Moisturizer
Publication:
Aesthetic Surgery Journal
Regenerating Skin Nectar
December 2020
Products:
Evaluating the Efficacy, Tolerability, and Outcomes of Topical Tripeptide/Hexapeptide Formulations Before and After Liposuction of the Medial Thighs
Publication:
The Aesthetic Society
TriHex Technology
Nov/Dec 2020
Products:
Combination Tripeptide/Hexapeptide Serum with 1540 nm Nonablative Fractional Laser for the Treatment of Striae Distensae: A Pilot Study
Publication:
Dermatology Case Report
INhance Post-Injection Serum
November 2020
Products:
New approaches to skin photodamage histology— Differentiating 'good' versus 'bad' Elastin
Publication:
Journal of Cosmetic Dermatology
TransFORM Body Treatment
November 2020
Products:
An Analysis of Patient-Reported Recovery Outcomes of Topical Tripeptide/Hexapeptide Formulations Utilized in a Prospective Randomized Double-Blind Split Neck and Body Study
Publication:
The Aesthetic Society
Regenerating Skin Nectar
Sept 2020
Products:
Tripeptide and hexapeptide topical as adjunct to nonablative fractional resurfacing for photodamage: A randomized splitface trial
Publication:
Journal of Cosmetic Dermatology
Regenerating Skin Nectar
Feb 2021
Products:
Prospective, Randomized, Comparative Study of the Cutaneous Effects of a Topical Body Treatment Compared to a Bland Moisturizer
Publication:
Regenerating Skin Nectar, TransFORM Body Treatment
May 2020
Products:
Gene Expression Changes in the Skin of Patients Undergoing Medial Thigh Liposuction With Pre-Surgical and Post-Surgical Application of Topical Products
Publication:
INhance Post-Injection Serum
March 2020
Products:
Developing a Topical Adjunct to Injectable Procedures
Publication:
JDD
TransFORM Body Treatment
January 2020
Products:
Topical Treatment with Tripeptide and Hexapeptide Following Body-Contouring Procedures Improved Patient-Reported Recovery Outcomes
Publication:
The Aesthetic Society
TransFORM Body Treatment
September 2019
Products:
A randomized double-blind trial evaluating the efficacy and tolerability of topical body treatment with TriHex Technology® combined with abdomen cryolipolysis or radiofrequency procedures
Publication:
Journal of Cosmetic Dermatology
Regenerating Skin Nectar
August 2019
Products:
Pre- and Post-Procedural Care Best Practices To Enhance Energy-Based Treatment Outcomes
Publication:
JDD
TriHex Technology
May 2019
Products:
A topical regimen improves skin healing and aesthetic outcomes when combined with a radiofrequency microneedling procedure
Publication:
Journal of Cosmetic Dermatology
TriHex Technology
April 2019
Products:
Preoperative Skin Conditioning: Extracellular Matrix Clearance and Skin Bed Preparation, A New Paradigm
Publication:
Aesthetic Surgery Journal
TransFORM Body Treatment
April 2019
Products:
A Double-Blind Randomized Controlled Trial Evaluating the Efficacy and Tolerability of a Topical Body Treatment in Combination With Cryolipolysis Procedures
Publication:
JDD
TransFORM Body Treatment
April 2019
Products:
Non-Surgical Fat Reduction and Topical Modulation of Adipose Tissue Physiology
Publication:
JDD
Restorative Skin Complex
June 2018
Products:
A single-center clinical trial to evaluate the efficacy of a tripeptide/hexapeptide antiaging regimen
Publication:
Dermatology Case Report
TriHex Technology
May/June 2018
Products:
ALASTIN SKINCARE® TAKES THEIR PROPRIETARY TRIHEX TECHNOLOGY® TO THE NEXT LEVEL
Publication:
PRIME
Regenerating Skin Nectar
May 2018
Products:
Effects of anhydrous gel with TriHex peptides on healing after hybrid laser resurfacing
Publication:
Restorative Eye Treatment
Mar 2018
Products:
A single-center, pilot study evaluating a novel TriHex peptide-and botanical-containing eye treatment compared to baseline
Publication:
Restorative Skin Complex
January 2018
Products:
A single-center clinical trial to evaluate the efficacy of a tripeptide/hexapeptide antiaging regimen
Publication:
Journal of Cosmetic Dermatology
Restorative Skin Complex
2018
Products:
A Tripeptide/Hexapeptide Anti-Aging Regimen that Targets Both Collagen and Elastin, and Improves both Physician and Subject Scoring of Facial Aesthetics
Publication:
Dermatology Case Reports
Regenerating Skin Nectar, Restorative Skin Complex
September 2017
Products:
Histological Changes Associated with Extracellular Matrix-Remodeling Topical Therapy
Publication:
Dermatology Case Report
Regenerating Skin Nectar
July 2017
Products:
Randomized, Split-Face/Decollete Comparative Trial of Procedure Enhancement System for Fractional non-Ablative Laser Resurfacing Treatment
Publication:
JDD
TriHex Technology
March 2017
Products:
A randomized, single-blinded trial of a tripeptide/hexapeptide healing regimen following laser resurfacing of the face
Publication:
Journal of Cosmetic Dermatology
Regenerating Skin Nectar
April 2016
Products:
Extracellular Matrix Modulation: Optimizing Skin Care and Rejuvenation Procedures
Publication:
JDD
Regenerating Skin Nectar, Restorative Skin Complex, Restorative Eye Treatment
Oct 2016
Products:
Recycling the Matrix
Publication:
The Aesthetic Guide
Regenerating Skin Nectar
Products:
A randomized, investigator -blinded trial of alastin topical healing regimen following ipl and/or pdl with q-switch-alexandrite and fractionated co2 laser resurfacing of the face
Publication:
Dermatology Case Report
Regenerating Skin Nectar, Restorative Skin Complex
Products:
Histological changes associated with extracellular matrix-remodeling topical therapy
Publication:
Dermatology Case Report
Regenerating Skin Nectar
Products:
A single–center, randomized, investigator-blinded comparative trial, topical proprietary Procedure Enhancement System (PES) vs. a basic regimen (bland ointment and cream) pre and post-fractional non-ablative laser resurfacing treatment to the face/décolleté.
Publication:
Dermatology Case Report
ALASTIN Skincare® develops innovative, scientifically tested and physician prescribed skin care products that correct, protect, and maintain healthy skin.
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